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1.
Orv Hetil ; 163(27): 1061-1065, 2022 Jul 03.
Article in English | MEDLINE | ID: covidwho-2264136

ABSTRACT

The Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) is an autolimited process, which can be caused by viral agents like Epstein-Barr virus, human herpes virus, HIV, B19 parvovirus, paromyxoviruses, SARS-CoV-2, Toxoplasma and Yersinia. The correct diagnosis is based on histological findings. A 45-year-old female patient presented in our ambulatory room with a unilateral neck mass, fever, dysphonia and dysphagia. The patient was double-tested positive for SARS-CoV-2 approximately 1 month before the symptoms started. Before examination, the nasopharyngeal rapid test for SARS-CoV-2 resulted negative. After hospitalization, intravenous antibiotic (Augmentin, 3 × 1.2 g; Klion, 2 × 100 mg) and steroid (Solu-Medrol, 2 × 125 mg) therapy were administered. The neck and chest CT described a right-sided retropharyngeal abscess with bilateral neck lympadenopathy. Urgent tracheotomy, neck dissection and lymph node biopsy were made. The intraoperative findings excluded the presence of the abscess. The histological findings confirmed the necrotizing histiocytic lymphadenitis. Despite of the fact that the Kikuchi-Fujimoto disease is autolimited, we can see that, in this particular case, the lymphadenopathy after the SARS-CoV-2 infection caused a life-threatening situation. The formed extratissular liquid imitated the image of a retropharyngeal abscess. In the searched worldwide literature, similar intervention for this type of process was not described. Tracheotomy, neck dissection and removing the lymph nodes as ,,trigger zones" caused the full recovery of the patient. In the future, we consider important proving and clarifying the correlation between SARS-CoV-2 and Kikuchi-Fujimoto disease. Orv Hetil. 2022; 163(27): 1061-1065.


Subject(s)
COVID-19 , Epstein-Barr Virus Infections , Histiocytic Necrotizing Lymphadenitis , Retropharyngeal Abscess , COVID-19/complications , COVID-19/diagnosis , Diagnosis, Differential , Epstein-Barr Virus Infections/diagnosis , Epstein-Barr Virus Infections/pathology , Female , Herpesvirus 4, Human , Histiocytic Necrotizing Lymphadenitis/complications , Histiocytic Necrotizing Lymphadenitis/diagnosis , Histiocytic Necrotizing Lymphadenitis/drug therapy , Humans , Lymph Nodes , Middle Aged , Retropharyngeal Abscess/diagnosis , Retropharyngeal Abscess/pathology , SARS-CoV-2
2.
BMJ Case Rep ; 13(12)2020 Dec 22.
Article in English | MEDLINE | ID: covidwho-999234

ABSTRACT

A 50-year-old Caucasian man presented to the emergency department during the early stages of the COVID-19 pandemic with a rapidly progressive facial swelling, fever, malaise and myalgia. The patient had recently travelled to a COVID-19-prevalent European country and was therefore treated as COVID-19 suspect. The day before, the patient sustained a burn to his left forearm after falling unconscious next to a radiator. A CT neck and thorax showed a parapharyngeal abscess, which was surgically drained, and the patient was discharged following an intensive care admission. He then developed mediastinitis 3 weeks post-discharge which required readmission and transfer to a cardiothoracic unit for surgical drainage. This report discusses the evolution of a deep neck space infection into a mediastinitis, a rare and life-threatening complication, despite early surgical drainage. This report also highlights the difficulties faced with managing patients during the COVID-19 pandemic.


Subject(s)
COVID-19 Drug Treatment , COVID-19 , Drainage , Mediastinitis , Patient Care Management/methods , Postoperative Complications , Retropharyngeal Abscess , Thoracic Surgical Procedures/methods , COVID-19/epidemiology , COVID-19/therapy , Catastrophic Illness/therapy , Diagnosis, Differential , Drainage/adverse effects , Drainage/methods , Humans , Infection Control/methods , Male , Mediastinitis/diagnosis , Mediastinitis/etiology , Mediastinitis/physiopathology , Mediastinitis/surgery , Middle Aged , Neck/diagnostic imaging , Neck/surgery , Postoperative Complications/diagnosis , Postoperative Complications/physiopathology , Postoperative Complications/surgery , Retropharyngeal Abscess/diagnosis , Retropharyngeal Abscess/physiopathology , Retropharyngeal Abscess/surgery , SARS-CoV-2 , Treatment Outcome
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